University of wisconsin-madison

Acute Infectious Endometritis

Acute infectious endometritis occurs most often in older mares which have had several foals. The uterine defenses which keep normal tract bacteria from infecting the uterus begin to breakdown. If the uterus is inflamed on or after day 5 of the cycle, the CL will regress because of PGF2a resulting from the inflamation. In addition, the early embryo will not be able to implant in the uterus and will die. Most mares with this condition will come into heat early.

Normal estrual uterine cytology

Diagnosis is made by collecting concurrent endometrial swabs and smear samples during early heat. These are then evaluated by bacteriological culture and cytology examinations. Positive cytology results include increased leukocytes in the uterus.

Treatment involves infusion of the uterus with antibiotics as indicated from the bacteriological culture results. The number of treatments required will depend on the individual mare but daily infusions for 3-5 days works well for most mares. Mares with poor vulvular conformation should have a Caslick's procedure.

normal estrual uterus cytology
Acute inflamation
lymphocytes in the uterine epithelium showing acute inflamation

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Extrinsic causes

Intrinsic causes