University of wisconsin-madison

Drugs for the Control of Reproduction

A variety of drugs have been developed to control reproduction of mares. These drugs are all either the natural hormone or synthetic versions of the hormone that is made to be more effective when given to a mare.

Hormone
Effect
Drug
PGF2a Regression of the CL
Induction of abortion
Lutalyse, Equimate, Estrumate, Synchrocept
Progesterone

suppression of estrus
synchronization of ovulation
pregnancy maintenance

ReguMate, progesterone in oil, P+ (long acting)
Estrogen

estrus behavior

estradiol-17-B
LH ovulation induction hCG, recombinant eLH
GnRH

hastens breeding season (transitional mares only) ovulation induction
treat low libido or sperm production in stallions

Deslorelin, Ovuplant, osmotic pumps
Oxytocin Parturition induction
expulsion of retained placenta
Oxytocin

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Cycling Mares