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Hormone Manipulation: Case 2 Whoops, you missed your big chance. The mare should come into heat 2-6 days after the second PGF2a shot depending on the size of the follicles on the ovary. Ovulation would occur in 5-7 days after the begining of estrus. If you can only get semen between June 5 - 9 then each of the following would be true. May 15 & 28 :
May 25 & June 7
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