Lecture
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Hormone Manipulation: Case 2

You have chosen to use Progesterone (Regumate) but first you must remember what it does.

Progesterone is produced by the CL and inhibits GnRH and thus ovulation.
True
False
A decrease in progesterone (select all that apply):
Choice 1 causes a decrease in GnRH
Choice 2 allows for the growth of follicles
Choice 3 allows for an increase in estrogen and behavioral estrus
Choice 4 directly causes ovulation

You come up with a plan!

Starting today (5/15) you will feed the mare Regumate for 14 days (the length of the luteal phase). On the last day (5/29) you plan to give the mare prostaglandin (Lutalyse) to ensure any remaining CL is regressed.

When you take the mare off the Regumate and give her Lutalyse, you would expect that (select all that apply):
Choice 1 she will come into estrus in 7 days.
Choice 2 she will ovulate in 2-3 days.
Choice 3 she will come into estrus in 3 - 4 days.
Choice 4 she will ovulate in 6 - 8 days.

When do you expect to breed the mare?

May 29 - 30

June 1 - 2

June 4 - 6