Animal Aciences > Faculty Index > Greaser

	Marion Greaser, Professor    Director of the Muscle Biology Laboratory                       80% Research, 20% Instruction, affiliate appointment in the Department of Anatomy Department of Animal Science; Muscle Biology Laboratory 1805 Linden Drive West Madison, WI 53706 Telephone: 608/262-1456 Fax: 608/265-3110 email: mgreaser@ansci.wisc.edu PubMed citations

Education:

B.S., Animal Science, Iowa State University 1960-1964
M.S., Biochemistry & Meat & Animal Science, joint, University of Wisconsin-Madison, Madison, Wisconsin 1964-1967
Ph.D., Biochemistry & Meat & Animal Science, joint, University of Wisconsin-Madison, Madison, Wisconsin 1967-1969
Postdoctorate, Muscle Biochemistry, Boston Biomedical Research Institute, Boston, MA 1969-1971
Assistant Professor, University of Wisconsin-Madison, 1971-1973
Associate Professor, University of Wisconsin-Madison,1973-1977
Professor,University of Wisconsin-Madison 1977-present
Director of Muscle Biology Laboratory, University of Wisconsin-Madison, 1997-present

Research Interests:

Structure and function of muscle proteins, muscle growth and protein assembly, postmortem changes in muscle proteins.

Awards:

American Meat Science Assoc.--Distinguished Research Award 1981
American Heart Assoc. of Wisconsin -- Outstanding Researcher Award 1985
American Heart Assoc. of Wisconsin - Professional Practice Award 1987
American Society of Animal Science – Award in Meat Research 2000
Who's Who in America 1986- present
Editorial Board - Journal of Food Science 1987-1992
Editorial Board - Meat Science 1992 - present
Editorial Board - Journal of Muscle Foods 1999 - 2002
NIH Physiology Study Section - 1997

Courses Taught

An Sci/Anat/Physiol 725 - Muscle Biology
An Sci 305 - Meat Science
Food Sci 514 - Food Chemistry II

Publications (of over 175 total)

Greaser, M.L. 2001. Identification of new repeating motifs in titin. Proteins 43:145-149.

K. Watanabe, P. Nair, D. Labeit, M. Kellermayer, M. Greaser, S. Labeit, and H. Granzier. 2002. Molecular mechanics of cardiac titin's PEVK and N2B spring elements. J. Biol. Chem. 277:11549-11558.

Harris, S.P., C.R. Bartley, T.A. Hacker, K.S. McDonald, M.L. Greaser, P.A. Powers, and R.L. Moss. 2002. Hypertrophic cardiomyopathy in myosin binding protein-C knockout mice. Circ. Res. 90:594-601.

Yamasaki, R., Y. Wu, M. McNabb, M. Greaser, S. Labeit, and H. Granzier. 2002. Protein kinase A phosphorylates the cardiac-specific N2B domain of titin's extensible region and modulates passive tension in rat cardiac myocytes. Circ. Res. 90:1181-1188.

Torrealba, J.R., E. Lozano, M. Griffin, S. Stoker, K. McDonald, M. Greaser, and M.R.Wolff. 2002. Maximal ATPase activity and calcium sensitivity of reconstituted myofilaments are unaltered by the fetal troponin T re-expressed during human heart failure. J. Mol. Cell. Cardiol. 34:797-805.

Greaser, M.L., M. Berri, C.M. Warren, and P.E. Mozdziak. 2002. Species variations in cDNA sequence and exon splicing patterns in the extensible I-band region of cardiac titin: relation to passive tension. J. Muscle Res. Cell Motil. 23:471-480.

Harris, S.P., W.T. Heller, M.L. Greaser, R.L. Moss, and J. Trewhella. 2003. Solution structure of heavy meromyosin by small-angle scattering. J. Biol. Chem. 278:6034-6040.

Huang, C., Q. Zhou, P. Liang, M. Hollander, F. Sheikh , X. Li, M. Greaser, G. D. Shelton, S. Evans, and J.Chen. 2003. Short or long isoforms of Cypher can rescue lethality resulting from loss of Cypher function. J. Biol. Chem. 278:7360-7365.

Warren, C.M., P.R. Krzesinski, and M.L. Greaser. 2003. Vertical agarose gel electrophoresis and electroblotting of high molecular weight proteins. Electrophoresis 24:1695-1702.

Warren, C.M., M. C. Jordan, K. P. Roos, P. R. Krzesinski, and M. L. Greaser. 2003. Titin isoform expression in normal and hypertensive myocardium. Cardiovasc. Res. 59:86-94.

Chad M. Warren, C.M. and M.L. Greaser. 2003. Method for cardiac myosin heavy chain separation by SDS gel electrophoresis. Anal. Biochem. 320:149-151.

Ilian, M.A., R. Bickerstaffe and M.L. Greaser. 2003. Postmortem changes in myofibrillar-bound calpain 3 revealed by immunofluorescence microscopy. Meat Sci. 66:231-240.

Trombitás, K., Y. Wu, M. McNabb, M. Greaser, M.S.Z. Kellermayer, S. Labeit, and H . Granzier. 2003. Molecular basis of passive stress-relaxation in human soleus fibers: assessment of the role of immunoglobulin-like domain unfolding. Biophys. J. 85:3142-3153.

Ringkob, T.P., D.R. Swartz, and M.L. Greaser. 2004.  Light microscopy/image analysis of thin filament lengths utilizing dual probes on beef, chicken and rabbit myofibrils. J. Anim. Sci. 82:1445-1453.

Warren, C.M., P. R. Krzesinski, K. S. Campbell, R. L. Moss, and M. L. Greaser. 2004. Titin isoform changes in rat myocardium during development.  Mech. Dev. 121:1301-1312.

Barash, I.A., L.Mathew, M. Lahey, M.L. Greaser, and R.L. Lieber. 2005.  Muscle LIM protein plays both structural and functional roles in skeletal muscle. Am. J. Physiol. Cell Physiol. 289: C1312-20.

Greaser, M.L., P.R. Krzesinski, C.M. Warren, B. Kirkpatrick, K.S. Campbell, and R. L. Moss. 2005. Developmental changes in rat cardiac titin/connectin: transitions in normal animals and in mutants with a delayed pattern of isoform transition. J. Mus. Res. & Cell Motil 26:325-332.

Sammel, L.M., J.R. Claus, M.L. Greaser and M.P. Richards. 2006. Investigation of mechanisms by which sodium citrate reduces the pink color defect in cooked ground turkey.  Meat Sci. 72:585-595.

Duan, Y., DeKeyser, J.G., Damodaran, S., and Greaser, M.L. 2006. Studies on titin PEVK peptides and their interaction. Arch. Biochem. Biophys. 454:16-25.